A true Christian with a heart big enough for all who needed him, Ramsay is now in the loving embrace of our Lord, where he is at peace with his oldest son, Ramsay Jr., his parents, Ronald MacDonald Downie and Mary Nicol, as well as his beloved dog, Red. It is with sadness that we tell you of the sudden passing on July 1, 2009, of our beloved Husband, Father, Brother, Grandfather, Uncle, but most of all Friend, Ramsay MacDonald Downie.
Celebration of Life or Memorial Options (without a casket or urn).Auditorium or Stadium – Celebration of Life / Memorial.Lodge or Private Club – Celebration of Life / Memorial.Park or Backyard – Celebration of Life / Memorial.Hotel or Restaurant – Celebration of Life / Memorial.Botanic Gardens – Celebration of Life / Memorial.Celebration of Life / Memorial in our Location or Church (with an Urn).Service / Celebration of Life in Our Location or Church.Service / Celebration of Life in Our Location.This abstract was presented at the 2019 ARVO Annual Meeting, held in Vancouver, Canada, April 28 - May 2, 2019. These findings support the utility of this novel parameter as a means for identifying and stratifying DED. More severe DED, based upon clinical classification, is associated with a greater reduction in tear extensional viscosity. Tear effective extensional viscosity is compromised in DED. There was a moderate positive correlation between effective tear film extensional viscosity and non-invasive tear break-up time ( r=0.32, p=0.001).
Tear extensional viscosity was negatively correlated with DED severity (r=-0.46, p<0.0001), indicating that a lower effective extensional viscosity is associated with more severe DED. Tears from eyes with DED had significantly (p<0.0001) lower effective extensional viscosity (mean ± SEM: 0.007 ± 0.0003 Pa.s) than healthy tears (0.01 ± 0.001 Pa.s). Correlations were determined using Pearson’s correlation coefficient ( r).Ĭontrol and DED participants had similar age and sex distributions (p>0.05). Following data normality testing, inter-group comparisons were analyzed using a student’s t-test. Basal tear samples (2 µl/eye) were non-invasively collected and tear effective extensional viscosity was quantified by a separate masked examiner. A composite severity score (from 0.0 to 4.0) was derived based upon a comprehensive anterior eye assessment, including quantification of dry eye symptoms (Ocular Surface Disease Index (OSDI) score), tear osmolarity, corneal sodium fluorescein and conjunctival lissamine green staining (Oxford scale), meibomian gland integrity, non-invasive tear break-up time and Schirmer test score. DED was diagnosed using the currently-accepted consensus Tear Film and Ocular surface Society (TFOS) International Dry Eye WorkShop II (DEWS II) criteria. This prospective, cross-sectional study involved 103 participants (n=43 with healthy tears (controls) and n=60 with DED). We investigated a novel approach, involving quantification of tear effective extensional viscosity, using acoustically-driven microfluidic extensional rheometry for identifying DED, relative to current standards of assessment. A major barrier to people with dry eye disease (DED) receiving optimal clinical care is the challenge in reliably diagnosing and assessing the severity of the condition.
0 kommentar(er)
